GPU Semiconductor Content

  • Nice slide from KLA.
  • So I tried just to put together this chart to show how different the GPU package is between 2015 & 2024. So of course, the B100 chip, the GPU introduced a few months ago, and this is not enough because Jensen has already introduced the next generation of GPU last week” (h/t The Transcript).

GLP-1s and Addiction

  • There is probably enough evidence now to suggest GLP-1s, like Ozempic, work to treat all kinds of addiction.
  • Why does this matter? “Addiction kills more Americans than cancer or heart disease but only 4% of people with substance use disorders currently receive medication.
  • The big breakthrough in this field will likely be the next generation of weight loss drugs, especially orals.

Concentration and Active Management

  • Rising stock market concentration is challenging for active managers because on average they own stocks with smaller market capitalizations than those in their benchmarks. That means when large-cap stocks do well relative to small-cap stocks, the percentage of mutual funds that outperform the benchmark tends to go down. When small caps outperform large caps, active managers outperform at a higher rate. Exhibit 7 shows this relationship from 1960 to 2023. The striped red dot shows the outcome for 2023.
  • Source: Mauboussin.
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