IRA and Pharma

  • Interesting set of company quotes on views about the impact of IRA on Medicare negotiating drug prices.
  • Most of the industry has launched multi-pronged lawsuits (including constitutional challenges) against this.
  • To read more transcripts from AlphaSense Expert Insights get a free two-week trial here [use work email].

AI and Healthcare

  • Healthcare is one area where the application of AI, in its LLM and other forms, could be enormous.
  • This nice article from AlphaSense Expert Insights explores the topic, mirroring the huge rise in expert calls in the sector mentioning the term.
  • It is not all areas that can be bent to the will of ML. As this piece argues, academic literature and the correspondent knowledge graph is both difficult and not that useful to program.
  • If you want to read some of these transcripts, you can grab a two-week free trial.

Regulatory Capture

  • Bill Gurley’s September 2023 talk “2,851 Miles.” is a very interesting read on this very important topic in economics and investing.
  • As a rule, regulation is acquired by the industry and is designed and operated primarily for its benefit.” I like to say, “Regulation is the friend of the incumbent.”

SEC New Short Disclosure Rules

  • SEC is increasing disclosure around shorts.
  • Investment managers that carry large short positions in equity securities will be required, within two weeks after each month, to report those positions and related short sale activity to the Commission. The threshold for reporting will be met when an investment manager’s short position in a particular equity security of a reporting issuer is at least $10 million or the equivalent of 2.5 percent or more of the total shares outstanding on average during a month.
  • Based upon the filings to the Commission, the Commission will make public, within four weeks after the end of each month, aggregated, anonymized data about the gross, end-of-month large short positions. The Commission also will publish the net aggregated daily activity data for each settlement day.
  • The UK (and EU) have good disclosures on shorts >0.5% of shares outstanding.

Clean Energy Cycle

  • As GMO points out – clean energy has gone through a classic hype cycle.
  • All the relative outperformance blow out has come off.
  • Yet, change could be afoot – especially as firms focus on profitability – as described in this excellent analysis from AlphaSense (need to sign up).
  • Government policy is helping – here is what GE said about the big incentives offered by the Inflation Reduction Act (IRA).
  • I know the IRA has created an eight year incentive, an incentive through 2030. That was enough of a long-term incentive for a few of the manufacturers that I know of that were making big decisions on supply chain changes, onshoring things, changing from China sources. In the absence of IRA incentives they would not happen. They would be small changes.

Razor and Razor Blades Strategy Was a Myth!

  • It is business lore now that Gillette originated the business strategy of selling cheap razor handles to lock in customers to relatively more expensive razor blades, or so the story goes, recreated in board rooms and strategy meetings around the world today.
  • However, as this paper shows, Gillette never actually pursued this strategy – even when patent protection meant their handles couldn’t be used with any other blade.
  • h/t The Diff.
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