Farnam Ackman Interview

  • Really interesting podcast interviewing Bill Ackman.
  • It is by Farnam Street’s Knowledge Project.
  • “One of the most influential things he [Buffet] said to me was if you want to be successful, all you need to do is look around the room and think about the classmate or classmates you most admire and what qualities they have and just decide to adopt those qualities. If you do that, your chances of being successful go up enormously.”
  • I actually think that people will be that much more desperate for human connection after this experience than they were before.
  • He is probably right on the last point – long human connection?

Greenlight Q1 2020 Letter

  • Latest investment letter from Einhorn’s Fund Greenlight Capital.
  • The fund is -21.5% in Q1 and down a futher -1.1% in April (despite the market rebound).
  • Interesting discussion of how, despite taking net from 74% to 15%, they still struggled with performance against a falling market.
  • Eninhorn’s value style is struggling in recent years and these markets. Despite this Greenlight is starting to market the fund again.
  • Letter includes interesting debate on inflation post-crisis, what to buy in that environment, his current holdings and shorts (incl TSLA), new positions. Always worth a read.

P/E vs. real rates and inflation

  • Two great charts from KKR Macro Insight.
  • They plot the markets trailing P/E ratio against CPI inflation (right hand side) and the 10-year real treasury yield (left hand side).
  • The data is from 1948 to today and sourced from BofAML
  • As real-rates go negative or inflation falls multiples tend to be lower.
  • KKR analysis suggests there isn’t some funny data skewing results here.
  • What about today? at the current real 10-year yield of -1.5% and inflation rate of 2.3% (likely to fall) the 17.5x P/E ratio for the market (since increased) stands out as too high.
  • These types of equity strategy charts are good to hang on to.

Innovation Lockdown

  • One of consequences of the lockdown, as Ben Evans writes, is that it is a forced experiment.
  • Many things are forced to change and it creates lots of opportunities especially in the way people work together.
  • tens of thousands of software engineers are cooped up at home getting frustrated with their current tools and wondering if they can spot some pain point, or mechanic, or small difference to the flow, and solve some opportunity that no-one ever quite realised was there.
  • Success can happen even if things look entrenched. The anecdote about Dropbox is telling – everyone told Drew Houston ‘there are dozens of these already’ and he kept replying ‘yes, but which ones do you use?’
  • There are already some interesting new ideas in the chat app market.

Global Consumer Pulse

  • Nice table from McKinsey on the global consumer.
  • It shows net intent to purchase a particular category by country.
  • Net intent = % who said they would increase purchases in the next two weeks compared to usual minus % who said they wouldn’t.
  • Interesting to see China/Korea recovering somewhat but not in all areas.

Covid Chart

  • A good chart from JP Morgan – Eye on the Market.
  • Eye on the Market itself is a great resource especially during the outbreak. Full of high frequency economic indicators.
  • This chart shows COVID infection trends (the colours) for each country but charted by percentage of world GDP.
  • One month ago nearly 50% of global GDP saw a rising COVID outbreak.
  • The picture is a lot better now as the red/orange are receding.
  • It turned in late March – around the time the market bottomed.

Third Point Q1 2020

  • Q1 letters in general are going to be very interesting to read.
  • Here is the latest letter for Q1 2020 from Third Point Capital.
  • Loeb’s fund is -16% in Q1.
  • They seem to have moved positions around a lot in March – mainly buying corporate credit exposure.
  • Lots of interesting stuff inside including a rant about socialising credit via Fed intervention.

Lockdown

  • A really excellent post from FT Alphaville trying to understand the lockdown.
  • They point to analysis by Sir David Spiegelhalter, former president of the Royal Statistical Society and co-chair of the Society’s Covid-19 task force.
  • He produced the pictured chart.
  • The pattern shows Covid deaths increase exponentially with age … this follows the pattern of normal risk. Whatever risks you’ve got, this just seems to exaggerate them — pump them up and pack a year’s worth of risk into a few weeks. Covid deaths are a fixed proportion of the people dying . ..”
  • Two extra points added to this are those exposed to excessive viral loads (healthcare workers) and the 10s of thousands of unnecessary deaths from less emergency care.
  • Moving away from the numbers – the moral discussion at the end is the most interesting part.

Covid Vaccine

  • A really brilliant article on the state of Covid vaccine development.
  • It gives a great overview and introduction into vaccines in general.
  • There are 115 vaccines in development (78 currently active).
  • There is a vast range of vaccine types (as the diagram shows). The article explains what all these types are.
  • We are only going to find out, in the end, by dosing people. Lots of people. With therapies targeting the immune system, there is in the end no other way to know, because of the complexities of the human immune response and its wide variation in the human population .. some of the steps are going to have to be done on a scale never before attemptedthere are going to have to be some shortcuts.
  • There is one thing that can’t be skipped – how long immunity lasts. This question can only be answered with time.
  • On safety – “Now you see the exact bind that vaccine development has always been in, because the whole point is to treat millions, even billions of people who are not currently sick, to protect them against disease while not doing more harm along the way by setting off the body’s fiercest and most alarming biological responses.
  • On manufacturing – “My guess is that scale-up and manufacturing could well be the biggest chance for the timelines mentioned earlier to blow up“.
  • There is a willingness to pre-fund manufacturing, across all these varied types of technology, before efficacy is established by Bill Gates and others.

Pharma R&D Productivity

  • It is taken for granted in the industry that pharmaceutical company productivity is in decline (here and here).
  • Indeed productivity has fallen by 8.4% per year since the 1950s.
  • However, these views are outdated (data tends to run to 2010), often fail to account for start-ups (i.e. by following a pre-existing cohort) and are an extrapolation of a trend.
  • The pictured chart is an updated graph of the number of new drugs or new molecular entities (NMEs) per $bn of R&D spend.
  • Interestingly it has actually been stable for much of the 2000s and can be explained in part by the industry having better information and how it is used. This article explains in depth.
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