Outsourcing in the biotech and pharma industry continues unabated, boosting contract research organisations (CRO) like IQIVIA, Labcorp etc.
Interestingly, consolidation has been a big feature of the industry, and this Stream expert call (sign up for free two weeks to access) suggests more is to come.
Interesting first hand account of how Monzo grew from nothing to 1 million users in three short years.
Tom credits – a great product (compared to competition) that was a delight to use, a brightly coloured card, and network effects – “if you had 3+ friends on Monzo when you joined, you had a 70% chance of being a WAU [weekly active user] by day 90, versus only a 50% chance if you didn’t have any friends on the platform.“
Strikes me as a very important move by the US towards “open access” academic research.
By 2026 all US federal agency funded research must be free to read immediately on publication.
This has been talked about for a very long time.
In a recent transcript from Stream by AlphaSense (sign up for two free weeks here), a former Elsevier Director, argued the effect on RELX business will be a “small negative” as they will find ways to charge for ancillary parts of research (reviews, data etc). The hit to smaller publishers will be worse.
The first comprehensive economic analysis measuring the impact of sanctions on economic activity in Russia.
The team relies on “using private Russian language and unconventional data sources including high frequency consumer data, cross-channel checks, releases from Russia’s international trade partners, and data mining of complex shipping data”.
Results are grim – “From our analysis, it becomes clear: business retreats and sanctions are catastrophically crippling the Russian economy.”
Meet one of the most dramatic changes in communication costs in history.
The introduction of the first modern postal system in Britain in 1840.
A 1839 Act of Parliament created the Uniform Penny Post – a single low postage rate and the first adhesive postage stamp, replacing a complex distance based system.
The results were monumental and, as this paper finds, also improved innovation.
Today, 73% of people in the UK consider post as essential or fairly important.
According to Morningstar data, inclusion into an index no longer attracts the usual rise (on announcement) and then fall in stock price.
“Indeed, the up-and-down trajectory that was once the fingerprint of the index inclusion effect now resembles a flat line that runs from announcement date through the weeks following inclusion in the S&P 500.“
This chart shows the performance of three groups of firms.
GAAP losers – firms where expenses exceed sales, but once an intangible investment adjustment is made they turn profitable. In other words they are investing.
Real losers – these are firms that even after the adjustment is made are still loss making.
Profitable firms – at the outset these firms are profitable i.e. sales exceed all expenses.
From 1980 – 2017, GAAP losers substantially outperformed
NB the outperformance vs. profitable firms really shows up post 1996. “The message is that the market ultimately recognizes and pays for intangible investments that create value, even if they create losses in the short term.“
This chart comes via Investment Talk, a brilliant curation of all manner of investment resources.
Footnote: Empirical Research Analysis, National Bureau of Economic Research. As of June 30, 2022. Cheapest quintile refers to the most undervalued 20% of stocks in an analysis of large-capitalization US stocks. Standard Deviation is a measure of dispersion of a data set from its mean. Prior to 1952, the spread is measured using the price-to-book data of the largest 1,500 stocks. Current Level refers to the valuation spread as of June 30, 2022 which is 0.4 standard deviations above the mean.
